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Anti-IDH3G Antibody

Boster Bio Anti-IDH3G Antibody catalog # A10370. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial; Isocitric dehydrogenase subunit gamma; NAD (+) -specific ICDH subunit gamma; IDH3G

Gene Name

IDH3G

UniProt

P51553

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide corresponding to residues170-215 in Human IDH3G.

Clonality

Polyclonal

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 96% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Regulatory subunit which plays a role in the allosteric regulation of the enzyme catalyzing the decarboxylation of isocitrate (ICT) into alpha-ketoglutarate. The heterodimer composed of the alpha (IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the alpha (IDH3A) and gamma (IDH3G) subunits, have considerable basal activity but the full activity of the heterotetramer (containing two subunits of IDH3A, one of IDH3B and one of IDH3G) requires the assembly and cooperative function of both heterodimers.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

42794 MW

Applications Notes

WB: 1:500-1:1000

Gene Name Synonym

Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial

Subcellular Location

Mitochondrion

Protein Name

Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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