Anti-Pre-mRNA-splicing factor RBM22 RBM22 Antibody
Boster Bio Anti-Pre-mRNA-splicing factor RBM22 RBM22 Antibody catalog # A10311. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Pre-mRNA-splicing factor RBM22; RNA-binding motif protein 22; Zinc finger CCCH domain-containing protein 16; RBM22; ZC3H16;199G4
Gene Name
RBM22
UniProt
Q9NW64
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human RBM22 (NP_060517.1) .
Clonality
Polyclonal
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Involved in the first step of pre-mRNA splicing. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle. Involved in both translocations of the nuclear SLU7 to the cytoplasm and the cytosolic calcium-binding protein PDCD6 to the nucleus upon cellular stress responses.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
46896 MW
Applications Notes
WB: 1:500-1:2000
Gene Name Synonym
Pre-mRNA-splicing factor RBM22
Subcellular Location
Nucleus. Cytoplasm. Mainly located in the nucleus. Translocated from the nucleus to the cytoplasm after heat shock cell treatment. May be shuttling between the nucleus and the cytosol.
Protein Name
Pre-mRNA-splicing factor RBM22
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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