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Anti-MXRA5 Antibody

Boster Bio Anti-MXRA5 Antibody catalog # A10306. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Matrix-remodeling-associated protein 5; Adhesion protein with leucine-rich repeats and immunoglobulin domains related to perlecan; Adlican; MXRA5

Gene Name

MXRA5

UniProt

Q9NR99

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide corresponding to residues in Human MXRA5.

Clonality

Polyclonal

Tissue Specificity

Highly expressed in kidney, also detected on liver and spleen (PubMed:27599751) . Expressed by proximal tubular cells of the kidney (at protein level) (PubMed:27599751) . Expression highly increases during chronic kidney disease and autosomal dominant polycystic kidney disease, where is detected in cysts (PubMed:27599751) .

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

In kidney, has anti-inflammatory and anti-fibrotic properties by limiting the induction of chemokines, fibronectin and collagen expression in response to TGB1 and pro-inflammatory stimuli.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

312150 MW

Applications Notes

WB: 1:500-1:1000

Gene Name Synonym

Matrix-remodeling-associated protein 5

Subcellular Location

Secreted

Protein Name

Matrix-remodeling-associated protein 5

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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