Anti-MXRA5 Antibody
Boster Bio Anti-MXRA5 Antibody catalog # A10306. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Matrix-remodeling-associated protein 5; Adhesion protein with leucine-rich repeats and immunoglobulin domains related to perlecan; Adlican; MXRA5
Gene Name
MXRA5
UniProt
Q9NR99
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to residues in Human MXRA5.
Clonality
Polyclonal
Tissue Specificity
Highly expressed in kidney, also detected on liver and spleen (PubMed:27599751) . Expressed by proximal tubular cells of the kidney (at protein level) (PubMed:27599751) . Expression highly increases during chronic kidney disease and autosomal dominant polycystic kidney disease, where is detected in cysts (PubMed:27599751) .
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
In kidney, has anti-inflammatory and anti-fibrotic properties by limiting the induction of chemokines, fibronectin and collagen expression in response to TGB1 and pro-inflammatory stimuli.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
312150 MW
Applications Notes
WB: 1:500-1:1000
Gene Name Synonym
Matrix-remodeling-associated protein 5
Subcellular Location
Secreted
Protein Name
Matrix-remodeling-associated protein 5
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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