Anti-Centromere protein I CENPI Antibody
Boster Bio Anti-Centromere protein I CENPI Antibody catalog # A10263. Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Centromere protein I; CENP-I; FSH primary response protein 1; Follicle-stimulating hormone primary response protein; Interphase centromere complex protein 19; Leucine-rich primary response protein 1; CENPI; FSHPRH1, ICEN19, LRPR1
Gene Name
CENPI
UniProt
Q92674
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from human protein at AA range: 10-90
Clonality
Polyclonal
Applications
WB, ELISA
Purification
CENPI antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/mL
Form
Liquid
Function
Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Required for the localization of CENPF, MAD1L1 and MAD2 (MAD2L1 or MAD2L2) to kinetochores. Involved in the response of gonadal tissues to follicle-stimulating hormone.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
86720 MW
Gene Name Synonym
Centromere protein I
Subcellular Location
Nucleus. Chromosome, centromere. Localizes exclusively in the centromeres. The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex.
Protein Name
Centromere protein I
Isotype
IgG
Contents
Liquid form in PBS containing 50% glycerol, and 0.02% sodium azide.
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