Anti-AP1M1 Antibody (Center)
Boster Bio Anti-AP1M1 Antibody (Center) (Catalog # A10072-2) . Tested in IF, WB, Flow Cytometry application (s) . This antibody reacts with Human.
Product Specifications
Background
The protein encoded by this gene is the medium chain of the trans-Golgi network clathrin-associated protein complex AP-1. The other components of this complex are beta-prime-adaptin, gamma-adaptin, and the small chain AP1S1. This complex is located at the Golgi vesicle and links clathrin to receptors in coated vesicles. These vesicles are involved in endocytosis and Golgi processing. Alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene. [provided by RefSeq].
Synonyms
AP-1 complex subunit mu-1, AP-mu chain family member mu1A, Adaptor protein complex AP-1 subunit mu-1, Adaptor-related protein complex 1 subunit mu-1, Clathrin assembly protein complex 1 mu-1 medium chain 1, Clathrin coat assembly protein AP47, Clathrin coat-associated protein AP47, Golgi adaptor HA1/AP1 adaptin mu-1 subunit, Mu-adaptin 1, Mu1A-adaptin, AP1M1, CLTNM
Gene Name
AP1M1
UniProt
Q9BXS5
Host
Rabbit
Reactivity
Human
Immunogen
This AP1M1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 205-234 amino acids from the Central region of human AP1M1.
Clonality
Polyclonal
Applications
IF, WB, Flow Cytometry
Field of Research
Microbiology, Signal Transduction, Viral process, Host-Virus Interaction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight
48587 Da
Subcellular Location
Golgi apparatus. Cytoplasmic vesicle, clathrin- coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex
Prediction Reactivity
Bovine, Mouse, Rat
Isotype
Rabbit IgG
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
