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Anti-DCI Antibody (C-term)

Boster Bio Anti-DCI Antibody (C-term) (Catalog # A09974-1) . Tested in Flow Cytometry, IHC-P, WB application (s) . This antibody reacts with Human.

Product Specifications

Background

DCI is a member of the hydratase/isomerase superfamily. The protein encoded is a key mitochondrial enzyme involved in beta-oxidation of unsaturated fatty acids. It catalyzes the transformation of 3-cis and 3-trans-enoyl-CoA esters arising during the stepwise degradation of cis-, mono-, and polyunsaturated fatty acids to the 2-trans-enoyl-CoA intermediates.

Synonyms

Enoyl-CoA delta isomerase 1, mitochondrial,2-trans-enoyl-CoA isomerase, Delta (3), Delta (2) -enoyl-CoA isomerase, D3, D2-enoyl-CoA isomerase, Dodecenoyl-CoA isomerase, ECI1, DCI

Gene Name

ECI1

UniProt

P42126

Host

Rabbit

Reactivity

Human

Immunogen

This DCI antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 275-302 amino acids from the C-terminal region of human DCI.

Clonality

Polyclonal

Tissue Specificity

Expressed in liver (at protein level) .

Applications

Flow Cytometry, IHC-P, WB

Field of Research

Cancer, Cardiovascular, Metabolism, Signal Transduction, Mitochondria

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

32816 Da

Subcellular Location

Mitochondrion matrix {ECO:0000250|UniProtKB:P23965}

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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