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Anti-EIF2S3 Antibody

Boster Bio Anti-EIF2S3 Antibody catalog # A09574-1. Tested in WB, IHC, ICC, IF, IP, ELISA applications. This antibody reacts with Human, Mouse.

Product Specifications

Background

Interacts with GTP and initiator methionyl-tRNA, translation initiation factor eIF2 forms a ternary complex that binds the 40S ribosome and then scans an mRNA to select the AUG start codon for protein synthesis[PMID: 9736774]. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B. EIF2S3 is the core subunit of the heterotrimeric eIF2 complex.[PMID:23063529]

Synonyms

EIF2G; EIF2; eIF 2gX; eIF 2gA; eIF 2 gamma X

Gene Name

EIF2S3

UniProt

P41091

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

E.coli-derived human EIF2S3 recombinant protein (Position: A175-D470) .

Clonality

Polyclonal

Applications

WB, IHC, ICC, IF, IP, ELISA

Purification

Immunogen affinity purified.

Concentration

500 μg/mL

Form

Liquid

Storage Conditions

12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.

Gene Name Synonym

Eukaryotic translation initiation factor 2 subunit gamma

Protein Name

Eukaryotic translation initiation factor 2 subunit 3

Contents

500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.

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