Anti-SNRPD3 Antibody
Boster Bio Anti-SNRPD3 Antibody catalog # A09533. Tested in WB applications. This antibody reacts with Human.
Product Specifications
Synonyms
Small nuclear ribonucleoprotein Sm D3; Sm-D3; snRNP core protein D3; SNRPD3
Gene Name
SNRPD3
UniProt
P62318
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide corresponding to residues in Human SNRPD3.
Clonality
Polyclonal
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Plays role in pre-mRNA splicing as core component of the SMN-Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (PubMed:11991638, PubMed:18984161, PubMed:19325628, PubMed:25555158, PubMed:26912367, PubMed:28502770, PubMed:28781166, PubMed:28076346) . Component of both the pre- catalytic spliceosome B complex and activated spliceosome C complexes (PubMed:11991638, PubMed:28502770, PubMed:28781166, PubMed:28076346) . Is also a component of the minor U12 spliceosome (PubMed:15146077) . As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing (By similarity) .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
13916 MW
Applications Notes
WB: 1:500-1:1000
Gene Name Synonym
Small nuclear ribonucleoprotein Sm D3
Subcellular Location
Cytoplasm, cytosol
Protein Name
Small nuclear ribonucleoprotein Sm D3
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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