Anti-GNL3L Antibody
Boster Bio Anti-GNL3L Antibody catalog # A09415. Tested in WB, IHC, IF, ELISA applications. This antibody reacts with Human, Mouse, Rat, Cat.
Product Specifications
Synonyms
Guanine nucleotide-binding protein-like 3-like protein; GNL3L
Gene Name
GNL3L
UniProt
Q9NVN8
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cat
Immunogen
The antiserum was produced against synthesized peptide derived from human GNL3L. AA range:71-120
Applications
WB, IHC, IF, ELISA
Purification
Immunogen affinity purified
Concentration
1 mg/mL
Form
Liquid
Function
Stabilizes TERF1 telomeric association by preventing TERF1 recruitment by PML. Stabilizes TERF1 protein by preventing its ubiquitination and hence proteasomal degradation. Does so by interfering with TERF1-binding to FBXO4 E3 ubiquitin-protein ligase. Required for cell proliferation. By stabilizing TRF1 protein during mitosis, promotes metaphase-to-anaphase transition. Stabilizes MDM2 protein by preventing its ubiquitination, and hence proteasomal degradation. By acting on MDM2, may affect TP53 activity. Required for normal processing of ribosomal pre-rRNA. Binds GTP. .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
65573 MW
Gene Name Synonym
Guanine nucleotide-binding protein-like 3-like protein
Subcellular Location
Nucleus, nucleolus .
Isotype
IgG
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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