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Anti-DC-LAMP LAMP3 Antibody

Boster Bio Anti-DC-LAMP LAMP3 Antibody catalog # A09406. Tested in WB, IHC, IF, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Lysosome-associated membrane glycoprotein 3; LAMP-3; Lysosomal-associated membrane protein 3; DC-lysosome-associated membrane glycoprotein; DC LAMP; Protein TSC403; CD208; LAMP3; DCLAMP, TSC403

Gene Name

LAMP3

UniProt

Q9UQV4

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide from human protein at AA range: 261-310

Clonality

Polyclonal

Tissue Specificity

Detected in tonsil interdigitating dendritic cells, in spleen, lymph node, Peyer's patches in the small instestine, in thymus medulla and in B-cells (at protein level) . Expressed in lymphoid organs and dendritic cells. Expressed in lung. Up-regulated in carcinomas of the esophagus, colon, rectum, ureter, stomach, breast, fallopian tube, thyroid and parotid tissues. .

Applications

WB, IHC, IF, ELISA

Purification

The antibody was affinity-purified from rabbit serum by affinity-chromatography using a specific immunogen.

Concentration

1 mg/mL

Form

Liquid

Function

May play a role in dendritic cell function and in adaptive immunity. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

44346 MW

Gene Name Synonym

Lysosome-associated membrane glycoprotein 3

Subcellular Location

Lysosome membrane ; Single- pass type I membrane protein . Cytoplasmic vesicle membrane ; Single-pass type I membrane protein . During dendritic cell maturation, detected on cytoplasmic vesicles (the MHC II compartment) that contain MHC II proteins, LAMP1, LAMP2 and LAMP3 (PubMed:9768752) . Detected on lysosomes in mature dendritic cells (PubMed:9768752) . .

Isotype

IgG

Contents

PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.

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