Anti-mRNA-capping enzyme RNGTT Antibody
Boster Bio Anti-mRNA-capping enzyme RNGTT Antibody catalog # A09317. Tested in WB, IF applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
MRNA-capping enzyme; HCAP1; HCE; Polynucleotide 5'-triphosphatase;3.1.3.33; mRNA 5'-triphosphatase; TPase; mRNA guanylyltransferase;2.7.7.50; GTP--RNA guanylyltransferase; GTase; RNGTT; CAP1A
Gene Name
RNGTT
UniProt
O60942
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant full length Human RNGTT.
Clonality
Polyclonal
Tissue Specificity
Isoform 1 and isoform 4 (at a lesser extent) are expressed in cerebrum, cerebellum, thyroid, lung, heart, liver, kidney, spleen, large intestine, testis, skin and muscle.
Applications
WB, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
68557 MW
Gene Name Synonym
MRNA-capping enzyme
Subcellular Location
Nucleus .
Protein Name
MRNA-capping enzyme
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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