Anti-Rabenosyn-5 RBSN Antibody
Boster Bio Anti-Rabenosyn-5 RBSN Antibody catalog # A09291. Tested in WB, ELISA, IHC applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
Rabenosyn-5 ;110 kDa protein; FYVE finger-containing Rab5 effector protein rabenosyn-5; RAB effector RBSN ; Zinc finger FYVE domain-containing protein 20; RBSN ; ZFYVE20
Gene Name
RBSN
UniProt
Q9H1K0
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human ZFYVE20. AA range:145-194
Applications
WB, ELISA, IHC
Purification
Immunogen affinity purified
Concentration
1 mg/mL
Form
Liquid
Function
Rab4/Rab5 effector protein acting in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Required for endosome fusion either homotypically or with clathrin coated vesicles. Plays a role in the lysosomal trafficking of CTSD/cathepsin D from the Golgi to lysosomes. Also promotes the recycling of transferrin directly from early endosomes to the plasma membrane. Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate (PtdInsP3) (PubMed:11062261, PubMed:11788822, PubMed:15020713) . Plays a role in the recycling of transferrin receptor to the plasma membrane (PubMed:22308388) . .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
88870 MW
Gene Name Synonym
Rabenosyn-5
Subcellular Location
Cell membrane; Lipid-anchor; Cytoplasmic side. Early endosome membrane ; Lipid-anchor. Enriched in endosomes that are in close proximity to clathrin-enriched regions at the cell surface. .
Isotype
IgG
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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