Anti-LEPREL1 P3H2 Antibody
Boster Bio Anti-LEPREL1 P3H2 Antibody catalog # A09235. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Prolyl 3-hydroxylase 2
Gene Name
P3H2
UniProt
Q8IVL5
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human LEPREL1 (NP_060662.2) .
Clonality
Polyclonal
Tissue Specificity
Expression localized to the epithelia of bile ducts and to the sacroplasm of heart muscle and skeletal muscle. In the pancreas, localized to a subpopulation of Langerhans islet cells and in the salivary gland, expressed in acinar cells (at protein level) (PubMed:15063763) . Expressed in adult heart, placenta, lung, liver, skeletal muscle and kidney (PubMed:15063763, PubMed:18487197) . Detected in fetal heart, spleen, lung, liver skeletal muscle and kidney (PubMed:18487197) .
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Prolyl 3-hydroxylase that catalyzes the post- translational formation of 3-hydroxyproline on collagens (PubMed:18487197) . Contributes to proline 3-hydroxylation of collagen COL4A1 and COL1A1 in tendons, the eye sclera and in the eye lens capsule (By similarity) . Has high activity with the type IV collagen COL4A1, and lower activity with COL1A1 (PubMed:18487197) . Catalyzes hydroxylation of the first Pro in Gly-Pro-Hyp sequences where Hyp is 4-hydroxyproline (PubMed:18487197) . Has no activity on substrates that lack 4- hydroxyproline in the third position (PubMed:18487197) .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
80984 MW
Applications Notes
WB: 1:500-1:2000
Gene Name Synonym
Prolyl 3-hydroxylase 2
Subcellular Location
Endoplasmic reticulum
Protein Name
Prolyl 3-hydroxylase 2
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
