Anti-SLC25A25 Antibody (N-term)
Boster Bio Anti-SLC25A25 Antibody (N-term) (Catalog # A09109) . Tested in IHC-P, WB application (s) . This antibody reacts with Human, Rat.
Product Specifications
Background
Calcium-dependent mitochondrial solute carrier. Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. May act as a ATP-Mg/Pi exchanger that mediates the transport of Mg-ATP in exchange for phosphate, catalyzing the net uptake or efflux of adenine nucleotides into or from the mitochondria.
Synonyms
Calcium-binding mitochondrial carrier protein SCaMC-2, Mitochondrial ATP-Mg/Pi carrier protein 3, Mitochondrial Ca (2+) -dependent solute carrier protein 3, Small calcium-binding mitochondrial carrier protein 2, Solute carrier family 25 member 25, SLC25A25, APC3, KIAA1896, MCSC3, SCAMC2
Gene Name
SLC25A25
UniProt
Q6KCM7
Host
Rabbit
Reactivity
Human, Rat
Immunogen
This SLC25A25 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-93 amino acids from the N-terminal region of human SLC25A25.
Clonality
Polyclonal
Tissue Specificity
Widely expressed. Expressed in fetal and adult liver, skeletal muscle, testis, ovary, hippocampus and caudate nucleus [Isoform 2]: Expression is restricted to kidney and lung.
Applications
IHC-P, WB
Field of Research
Metabolism, Signal Transduction, Mitochondria
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Electroneutral antiporter that most probably mediates the transport of adenyl nucleotides through the inner mitochondrial membrane. Originally identified as an ATP-magnesium/inorganic phosphate antiporter, it could have a broader specificity for adenyl nucleotides. By regulating the mitochondrial matrix adenyl nucleotide pool could adapt to changing cellular energetic demands and indirectly regulate adenyl nucleotide-dependent metabolic pathways.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight
52663 Da
Subcellular Location
Mitochondrion inner membrane; Multi-pass membrane protein
Prediction Reactivity
Zebrafish, Bovine, Mouse, Xenopus
Isotype
Rabbit IgG
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
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