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Anti-ASAP2/Pag3 Antibody

Boster Bio Anti-ASAP2/Pag3 Antibody (Catalog# A09026) . Tested in WB application (s) . This antibody reacts with Human.

Product Specifications

Synonyms

Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2; Development and differentiation-enhancing factor 2; Paxillin-associated protein with ARF GAP activity 3; PAG3; Pyk2 C-terminus-associated protein; PAP; ASAP2; DDEF2, KIAA0400

Gene Name

ASAP2

UniProt

O43150

Host

Rabbit

Reactivity

Human

Immunogen

A partial length recombinant ASAP2 protein (amino acids 500-760)

Clonality

Polyclonal

Tissue Specificity

Detected in heart, brain, placenta, kidney, monocytes and pancreas.

Applications

WB

Field of Research

Actin Assembly, Actin, etc., Cytoskeleton, Cytoskeleton/ECM, Microfilaments, Signal Transduction

Purification

Protein A Chromatography

Concentration

0.5-1mg/mL, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Activates the small GTPases ARF1, ARF5 and ARF6. Regulates the formation of post-Golgi vesicles and modulates constitutive secretion. Modulates phagocytosis mediated by Fc gamma receptor and ARF6. Modulates PXN recruitment to focal contacts and cell migration. .

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Observed Molecular Weight

111651 MW

Applications Notes

Western blot: 2-4 μg/ml

Gene Name Synonym

Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2

Subcellular Location

Cytoplasm. Golgi apparatus, Golgi stack membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Colocalizes with F-actin and ARF6 in phagocytic cups.

Protein Name

Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2

Isotype

Rabbit IgG

Contents

100 μ g in 200 μ l PBS containing 0.05% BSA and 0.05% sodium azide.

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