Anti-SLC25A23 Antibody

Calcium-binding mitochondrial carrier protein SCaMC-3; Mitochondrial ATP-Mg/Pi carrier protein 2; Mitochondrial Ca (2+) -dependent solute carrier protein 2; Small calcium-binding mitochondrial carrier protein 3; Solute carrier family 25 member 23; SLC25A23; APC2, MCSC2, SCAMC3

Present in various cell lines (at protein level) . Expressed at low levels in most tissues examined, with highest expression in brain, skeletal muscle and pancreas.

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Calcium-dependent mitochondrial solute carrier. Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane (PubMed:15123600) . May act as a ATP-Mg/Pi exchanger that mediates the transport of Mg-ATP in exchange for phosphate, catalyzing the net uptake or efflux of adenine nucleotides into or from the mitochondria (PubMed:15123600) . Acts as a regulator of mitochondrial calcium uptake via interaction with MCU and MICU1 (PubMed:24430870) .