Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-SAMSN SAMSN1 Antibody

Boster Bio Anti-SAMSN SAMSN1 Antibody (Catalog # A08977) . Tested in ELISA, WB, ICC, IF applications. This antibody reacts with Human.

Product Specifications

Background

SAMSN (HACS1) is a member of a novel gene family of putative adaptors and scaffold proteins containing SH3 and SAM (sterile alpha motif) domains. It encodes a 441 amino acid protein that is differentially expressed in hematopoietic cells and malignancies including myeloid leukemia, lymphoma, and myeloma. SAMSN has restricted expression in human tissues. It has been shown to be up-regulated by B cell activation signals and is a participant in B cell activation and differentiation. SAMSN is an immunoinhibitory adaptor that might be a useful target for immune suppression therapy.

Synonyms

SLy2, HACS1, NASH1, SASH2, SH3D6B, SAM domain-containing protein SAMSN-1, Hematopoietic adaptor containing SH3 and SAM domains 1

Gene Name

SAMSN1

UniProt

Q9NSI8

Host

Rabbit

Reactivity

Human

Cross Reactivity

At least two isoforms of SAMSN are known to exist.

Immunogen

Rabbit polyclonal SAMSN antibody was raised against an 18 amino acid peptide near the carboxy terminus of human SAMSN. The immunogen is located within the last 50 amino acids of SAMSN.

Clonality

Polyclonal

Tissue Specificity

Detected in peripheral blood B-cells (at protein level) . Detected in spleen, liver and peripheral blood.

Applications

ELISA, WB, ICC, IF

Field of Research

Immunology

Purification

SAMSN Antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

Negative regulator of B-cell activation. Down-regulates cell proliferation (in vitro) . Promotes RAC1-dependent membrane ruffle formation and reorganization of the actin cytoskeleton. Regulates cell spreading and cell polarization. Stimulates HDAC1 activity. Regulates LYN activity by modulating its tyrosine phosphorylation (By similarity) .

Storage Conditions

SAMSN antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Observed Molecular Weight

41708 MW

Gene Name Synonym

SAM domain, SH3 domain and nuclear localization signals 1

Subcellular Location

Nucleus

Prediction Reactivity

Mouse

Protein Name

SAM domain, SH3 domain and nuclear localization signals 1

Isotype

IgG

Contents

SAMSN Antibody is supplied in PBS containing 0.02% sodium azide.

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Mouse Corneal Fibroblast Cell Complete Medium
MBS2577009-01 100 mL

Mouse Corneal Fibroblast Cell Complete Medium

Ask
View Details
Mouse Corneal Fibroblast Cell Complete Medium
MBS2577009-02 4x 125 mL

Mouse Corneal Fibroblast Cell Complete Medium

Ask
View Details
ABCB1 Knockout AGS Polyclonal Cells
ARG35275 1 Million

ABCB1 Knockout AGS Polyclonal Cells

Ask
View Details
Human/Mouse/Rat Activin A (bA Subunit) MAb (Clone 69403)
MAB3381-SP 25 µg

Human/Mouse/Rat Activin A (bA Subunit) MAb (Clone 69403)

Ask
View Details
Frizzled 4 (FZD4) (NM_012193) Human Tagged ORF Clone Lentiviral Particle
RC217286L3V 200 µL

Frizzled 4 (FZD4) (NM_012193) Human Tagged ORF Clone Lentiviral Particle

Ask
View Details
Rabbit Polyclonal Bmf Antibody
NBP3-00165-50ul 50 µL

Rabbit Polyclonal Bmf Antibody

Ask
View Details