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Anti-IFT74 Antibody

Boster Bio Anti-IFT74 Antibody catalog # A08931. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Intraflagellar transport protein 74 homolog; Capillary morphogenesis gene 1 protein; CMG-1; Coiled-coil domain-containing protein 2; IFT74; CCDC2, CMG1

Gene Name

IFT74

UniProt

Q96LB3

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human IFT74 (NP_001092694.1) .

Clonality

Polyclonal

Tissue Specificity

Highly expressed in adult and fetal kidney and expressed at lower level in adult heart, placenta, lung, liver and pancreas, and in fetal heart, lung and liver. Little to no expression was detected in adult brain and skeletal muscle or in fetal brain, thymus and spleen.

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Component of the intraflagellar transport (IFT) complex B: together with IFT81, forms a tubulin-binding module that specifically mediates transport of tubulin within the cilium. Binds beta-tubulin via its basic region. Required for ciliogenesis.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

69239 MW

Applications Notes

WB: 1:1000-1:3000

Gene Name Synonym

Intraflagellar transport protein 74 homolog

Subcellular Location

Cell projection, cilium. Cytoplasmic vesicle. Localizes along primary cilia at interphase and around the basal body/centriole at interphase and mitosis.

Protein Name

Intraflagellar transport protein 74 homolog

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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