Anti-TTC37/SKIC3 Antibody
Boster Bio Anti-TTC37/SKIC3 Antibody catalog # A08710. Tested in WB, IHC, ICC, IF, IP, ELISA applications. This antibody reacts with Human, Mouse.
Product Specifications
Background
TTC37 (tetratricopeptide repeat protein 37), also named as Thespin, encodes 1,564 amino acid protein that contains twenty tetratricopeptide (TPR) repeats. TPR repeat-containing motifs are found in a variety of proteins and may mediate protein-protein interactions and chaperone activity. Although not expressed in liver, TTC37 is a widely expressed protein with highest levels of expression in vascular tissues, lymph node, pituitary, lung and intestine. TTC37 is a component of the SKI complex which is thought to be involved in exosome-mediated RNA decay and associates with transcriptionally active genes in a manner dependent on PAF1 complex (PAF1C) . Defects in TTC37 are associated with Trico-Hepato-Enteric (THE) syndrome.
Synonyms
TPR repeat protein 37; Thespin; Superkiller complex protein 3; SKIC3; Ski3
Gene Name
SKIC3
UniProt
Q6PGP7
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
E.coli-derived human TTC37/SKIC3 recombinant protein (Position: A1217-S1562) .
Clonality
Polyclonal
Applications
WB, IHC, ICC, IF, IP, ELISA
Purification
Immunogen affinity purified.
Concentration
500 μg/mL
Form
Liquid
Storage Conditions
12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.
Gene Name Synonym
SKI3 subunit of superkiller complex
Protein Name
Superkiller complex protein 3
Contents
500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.
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