Anti-YY1-associated factor 2 YAF2 Antibody
Boster Bio Anti-YY1-associated factor 2 YAF2 Antibody catalog # A08678. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
YY1-associated factor 2; YAF2
Gene Name
YAF2
UniProt
Q8IY57
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to residues in Human YAF2.
Clonality
Polyclonal
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Binds to MYC and inhibits MYC-mediated transactivation. Also binds to MYCN and enhances MYCN-dependent transcriptional activation. Increases calpain 2-mediated proteolysis of YY1 in vitro. Component of the E2F6.com-1 complex, a repressive complex that methylates 'Lys-9' of histone H3, suggesting that it is involved in chromatin-remodeling.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
19901 MW
Applications Notes
WB: 1:500-1:1000
Gene Name Synonym
YY1-associated factor 2
Subcellular Location
Nucleus
Protein Name
YY1-associated factor 2
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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