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Anti-Human-AHCTF1 (S1232) Antibody

Boster Bio Anti-Human-AHCTF1 (S1232) Antibody (Catalog # A08604) . Tested in WB application (s) . This antibody reacts with Human.

Product Specifications

Background

Required for the assembly of a functional nuclear pore complex (NPC) on the surface of chromosomes as nuclei form at the end of mitosis. May initiate NPC assembly by binding to chromatin and recruiting the Nup107-160 subcomplex of the NPC. Also required for the localization of the Nup107-160 subcomplex of the NPC to the kinetochore during mitosis and for the completion of cytokinesis.

Synonyms

Protein ELYS, Embryonic large molecule derived from yolk sac, Protein MEL-28, Putative AT-hook-containing transcription factor 1, AHCTF1, ELYS, TMBS62

Gene Name

AHCTF1

UniProt

Q8WYP5

Host

Rabbit

Reactivity

Human

Immunogen

This antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1210-1260 amino acids from human.

Clonality

Polyclonal

Applications

WB

Field of Research

Cardiovascular, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Required for the assembly of a functional nuclear pore complex (NPC) on the surface of chromosomes as nuclei form at the end of mitosis. May initiate NPC assembly by binding to chromatin and recruiting the Nup107-160 subcomplex of the NPC. Also required for the localization of the Nup107-160 subcomplex of the NPC to the kinetochore during mitosis and for the completion of cytokinesis.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

252498 Da

Applications Notes

WB: 1:1000

Subcellular Location

Cytoplasm {ECO:0000250|UniProtKB:Q8CJF7}. Nucleus. Nucleus envelope Nucleus matrix. Chromosome, centromere, kinetochore Nucleus, nucleoplasm. Nucleus, nuclear pore complex. Note=Localizes to the nuclear pore complex (NPC) throughout interphase. Localizes to the kinetochore from prophase, and this appears to require the Nup107-160 subcomplex of the NPC. Localizes to the periphery of chromatin from late anaphase.

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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