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Anti-DEPDC1 Antibody (N-term)

Boster Bio Anti-DEPDC1 Antibody (N-term) (Catalog # A08594) . Tested in IHC-P, WB application (s) . This antibody reacts with Human.

Product Specifications

Synonyms

DEP domain-containing protein 1A, DEPDC1, DEPDC1A

Gene Name

DEPDC1

UniProt

Q5TB30

Host

Rabbit

Reactivity

Human

Immunogen

This DEPDC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-38 amino acids from the N-terminal region of human DEPDC1.

Clonality

Polyclonal

Tissue Specificity

Expressed in testis. Up-regulated in bladder cancer cells (at protein level) .

Applications

IHC-P, WB

Field of Research

Cancer

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

May be involved in transcriptional regulation as a transcriptional corepressor. The DEPDC1A-ZNF224 complex may play a critical role in bladder carcinogenesis by repressing the transcription of the A20 gene, leading to transport of NF-KB protein into the nucleus, resulting in suppression of apoptosis of bladder cancer cells.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

92960 Da

Subcellular Location

Nucleus. Note=Colocalizes with ZNF224 at the nucleus

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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