Anti-LTB4DH (L105) PTGR1 Antibody
Boster Bio Anti-LTB4DH (L105) PTGR1 Antibody catalog # A08587. Tested in WB applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
Prostaglandin reductase 1; PRG-1;1.3.1.-;15-oxoprostaglandin 13-reductase;1.3.1.48; NADP-dependent leukotriene B4 12-hydroxydehydrogenase;1.3.1.74; PTGR1; LTB4DH
Gene Name
PTGR1
UniProt
Q14914
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthetic peptide, corresponding to amino acids 72-123 of Human LTB4DH.
Clonality
Polyclonal
Tissue Specificity
High expression in the kidney, liver, and intestine but not in leukocytes.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-oxo-PGE1, 15-oxo-PGE2 and 15-oxo-PGE2-alpha. Has no activity towards PGE1, PGE2 and PGE2-alpha (By similarity) . Catalyzes the conversion of leukotriene B4 into its biologically less active metabolite, 12-oxo-leukotriene B4. This is an initial and key step of metabolic inactivation of leukotriene B4. .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
35870 MW
Applications Notes
WB: 1:500-1:1000
Gene Name Synonym
Prostaglandin reductase 1
Subcellular Location
Cytoplasm.
Protein Name
Prostaglandin reductase 1
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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