Anti-ULK4 Antibody

Boster Bio Anti-ULK4 Antibody (Catalog # A08552) . Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse.

Product Specifications

Background

ULK4 belongs to the Ser/Thr protein kinase superfamily and plays a role in the ATP-dependent phosphorylation of target proteins (1) . Knockout of ULK genes results in a severe defect in the autophagy pathway (2) . ULK4, like the other Unc-51-like kinases such as ULK1, ULK2 and ULK3, is highly conserved among eukaryotes (3) . ULK4 has been implicated as a gene involved in the development of hydrocephalus (3) . This neurologic disorder is being used in animal models to elucidate factors responsible for the excessive accumulation of cerebrospinal fluid in hydrocephalic humans (4) .

Synonyms

FAM7C1, REC01035Unc-51-like kinase 4

Gene Name

ULK4

UniProt

Q96C45

Host

Rabbit

Reactivity

Human, Mouse

Cross Reactivity

ULK4 antibody is human and mouse reactive. Multiple isoforms of ULK4 are known to exist.

Immunogen

ULK4 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human ULK4. The immunogen is located within amino acids 1120 - 1170 of ULK4.

Clonality

Polyclonal

Tissue Specificity

Expressed in the brain, mainly in postmitotic neurons, including GABAergic neurons, but not in astrocytes (at protein level) .

Applications

ELISA, WB, IHC-P, IF

Field of Research

Autophagy

Purification

ULK4 antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

May be involved in the remodeling of cytoskeletal components, such as alpha-tubulin, and in this way regulates neurite branching and elongation, as well as cell motility.

Storage Conditions

ULK4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Observed Molecular Weight

142442 MW

Gene Name Synonym

Unc-51 like kinase 4

Protein Name

Unc-51 like kinase 4

Isotype

IgG

ULK4 antibody is supplied in PBS containing 0.02% sodium azide.

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Anti-ULK4 Antibody

Product Specifications

Background

Synonyms

Gene Name

UniProt

Host

Reactivity

Cross Reactivity

Immunogen

Clonality

Tissue Specificity

Applications

Field of Research

Purification

Concentration

Form

Function

Storage Conditions

Observed Molecular Weight

Gene Name Synonym

Protein Name

Isotype

Contents

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