Anti-THAP11 Antibody
Boster Bio Anti-THAP11 Antibody (Catalog # A08519) . Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Background
The THAP domain-contining protein 11 (THAP11), also known as Ronin, is an essential factor involved in embryonic stem (ES) cell pluripotency and cell growth (1) . THAP 11 contains a THAP domain, a conserved DNA-binding domain common to many proteins associated with chromatin modification and gene expression silencing, and has striking similarity to the site-specific DNA-binding domain (DBD) of Drosophila P element transposases (2) . THAP11 can also negatively regulate CD44 v6 expression through its interaction with the poly (rC) binding protein PCBP1 (3) .
Synonyms
RONIN, CTG-B43a, CTG-B45d, HRIHFB2206, THAP domain-containing protein 11
Gene Name
THAP11
UniProt
Q96EK4
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
THAP11 antibody is human, mouse and rat reactive.
Immunogen
THAP11 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human THAP11. The immunogen is located within the last 50 amino acids of THAP11.
Clonality
Polyclonal
Applications
ELISA, WB
Field of Research
Stem Cells
Purification
THAP11 antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL
Form
Liquid
Function
Transcriptional repressor that plays a central role for embryogenesis and the pluripotency of embryonic stem (ES) cells. Sequence-specific DNA-binding factor that represses gene expression in pluripotent ES cells by directly binding to key genetic loci and recruiting epigenetic modifiers (By similarity) . .
Storage Conditions
THAP11 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Observed Molecular Weight
34455 MW
Gene Name Synonym
THAP domain containing 11
Subcellular Location
Nucleus
Prediction Reactivity
Bovine
Protein Name
THAP domain containing 11
Isotype
IgG
Contents
THAP11 antibody is supplied in PBS containing 0.02% sodium azide.
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