Anti-HECTD1 Antibody
Boster Bio Anti-HECTD1 Antibody catalog # A08428. Tested in WB applications. This antibody reacts with Human.
Product Specifications
Synonyms
E3 ubiquitin-protein ligase HECTD1;2.3.2.26
Gene Name
HECTD1
UniProt
Q9ULT8
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant fusion protein of human HECTD1 (NP_056197.3) .
Clonality
Polyclonal
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates 'Lys-63'-linked polyubiquitination of HSP90AA1 which leads to its intracellular localization and reduced secretion. Negatively regulating HSP90AA1 secretion in cranial mesenchyme cells may impair their emigration and may be essential for the correct development of the cranial neural folds and neural tube closure.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
289384 MW
Applications Notes
WB: 1:500-1:2000
Gene Name Synonym
E3 ubiquitin-protein ligase HECTD1
Protein Name
E3 ubiquitin-protein ligase HECTD1
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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