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Anti-HECTD1 Antibody

Boster Bio Anti-HECTD1 Antibody catalog # A08428. Tested in WB applications. This antibody reacts with Human.

Product Specifications

Synonyms

E3 ubiquitin-protein ligase HECTD1;2.3.2.26

Gene Name

HECTD1

UniProt

Q9ULT8

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant fusion protein of human HECTD1 (NP_056197.3) .

Clonality

Polyclonal

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates 'Lys-63'-linked polyubiquitination of HSP90AA1 which leads to its intracellular localization and reduced secretion. Negatively regulating HSP90AA1 secretion in cranial mesenchyme cells may impair their emigration and may be essential for the correct development of the cranial neural folds and neural tube closure.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

289384 MW

Applications Notes

WB: 1:500-1:2000

Gene Name Synonym

E3 ubiquitin-protein ligase HECTD1

Protein Name

E3 ubiquitin-protein ligase HECTD1

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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