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Anti-ARHGAP18 Antibody

Boster Bio Anti-ARHGAP18 Antibody catalog # A08418. Tested in WB, IHC, IF, ELISA applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Rho GTPase-activating protein 18; MacGAP ; Rho-type GTPase-activating protein 18; ARHGAP18

Gene Name

ARHGAP18

UniProt

Q8N392

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human RHG18. AA range:517-566

Applications

WB, IHC, IF, ELISA

Purification

Immunogen affinity purified

Concentration

1 mg/mL

Form

Liquid

Function

Rho GTPase activating protein that suppresses F-actin polymerization by inhibiting Rho. Rho GTPase activating proteins act by converting Rho-type GTPases to an inactive GDP-bound state (PubMed:21865595) . Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation. Acts downstream of YAP1 and inhibits actin polymerization, which in turn reduces nuclear localization of YAP1 (PubMed:25778702) . Regulates cell shape, spreading, and migration (PubMed:21865595) . .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

74977 MW

Gene Name Synonym

Rho GTPase-activating protein 18

Subcellular Location

Cytoplasm .

Isotype

IgG

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

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