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Anti-Metalloreductase STEAP2 STEAP2 Antibody

Boster Bio Anti-Metalloreductase STEAP2 STEAP2 Antibody (Catalog # A08410) . Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse.

Product Specifications

Background

The six-transmembrane epithelial antigen of prostate 2 (STEAP2) is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. Similar to two other members of the STEAP family (STEAP 3 and STEAP4), STEAP2 promotes both iron and copper reduction. STEAP2 expression in transfected cells also correlated with iron or copper uptake, suggesting that the STEAP family of proteins may function to stimulate iron and copper uptake. STEAP2 is widely expressed in many tissues in the plasma membrane, but is most highly expressed in prostate. At least three isoforms of STEAP2 are known to exist.

Synonyms

STMP, IPCA1, PUMPCn, STAMP1, PCANAP1, UNQ6507/PRO23203, Metalloreductase STEAP2, Prostate cancer-associated protein 1

Gene Name

STEAP2

UniProt

Q8NFT2

Host

Rabbit

Reactivity

Human, Mouse

Cross Reactivity

This STEAP2 antibody does not cross-react with other STEAP proteins.

Immunogen

STEAP2 antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human STEAP2. The immunogen is located within the last 50 amino acids of STEAP2.

Clonality

Polyclonal

Tissue Specificity

Expressed at high levels in prostate and at significantly lower levels in heart, brain, kidney, pancreas, and ovary.

Applications

ELISA, WB, IHC-P, IF

Field of Research

Homeostasis

Purification

STEAP2 Antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

Metalloreductase that has the ability to reduce both Fe (3+) to Fe (2+) and Cu (2+) to Cu (1+) . Uses NAD (+) as acceptor (By similarity) . .

Storage Conditions

STEAP2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Observed Molecular Weight

56056 MW

Gene Name Synonym

Six transmembrane epithelial antigen of the prostate 2

Subcellular Location

Endosome membrane ; Multi-pass membrane protein . Cell membrane

Protein Name

Six transmembrane epithelial antigen of the prostate 2

Isotype

IgG

Contents

STEAP2 Antibody is supplied in PBS containing 0.02% sodium azide.

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