Anti-CREBL1 Antibody (C-term)
Boster Bio Anti-CREBL1 Antibody (C-term) (Catalog # A08395-1) . Tested in IHC-P, WB application (s) . This antibody reacts with Human, Hamster, Mouse.
Product Specifications
Background
CREBL1 is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum; however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus.
Synonyms
Cyclic AMP-dependent transcription factor ATF-6 beta, cAMP-dependent transcription factor ATF-6 beta, Activating transcription factor 6 beta, ATF6-beta, Protein G13, cAMP response element-binding protein-related protein, Creb-rp, cAMP-responsive element-binding protein-like 1, Processed cyclic AMP-dependent transcription factor ATF-6 beta, ATF6B, CREBL1, G13
Gene Name
ATF6B
UniProt
Q99941
Host
Rabbit
Reactivity
Human, Hamster, Mouse
Immunogen
This CREBL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 560-589 amino acids from the C-terminal region of human CREBL1.
Clonality
Polyclonal
Tissue Specificity
Ubiquitous.
Applications
IHC-P, WB
Field of Research
Apoptosis
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
1125694411256944
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight
76709 Da
Subcellular Location
Endoplasmic reticulum membrane; Single-pass type II membrane protein
Isotype
Rabbit IgG
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
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