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Anti-Granzyme M GZMM Antibody

Boster Bio Anti-Granzyme M GZMM Antibody catalog # A08286. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Granzyme M;3.4.21.-; Met-1 serine protease; Hu-Met-1; Met-ase; Natural killer cell granular protease; GZMM; MET1

Gene Name

GZMM

UniProt

P51124

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide corresponding to residues in Human GZMM.

Clonality

Polyclonal

Tissue Specificity

Highly and constitutively expressed in activated natural killer (NK) cells.

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Cleaves peptide substrates after methionine, leucine, and norleucine. Physiological substrates include EZR, alpha- tubulins and the apoptosis inhibitor BIRC5/Survivin. Promotes caspase activation and subsequent apoptosis of target cells.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

27545 MW

Applications Notes

WB: 1:500-1:1000

Gene Name Synonym

Granzyme M

Subcellular Location

Secreted. Cytoplasmic granule. Granules of large granular lymphocytes.

Protein Name

Granzyme M

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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