Anti-NSFL1 cofactor p47 NSFL1C Antibody
Boster Bio Anti-NSFL1 cofactor p47 NSFL1C Antibody catalog # A08116. Tested in WB, IF applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
NSFL1 cofactor p47; UBX domain-containing protein 2C; p97 cofactor p47; NSFL1C; UBXN2C
Gene Name
NSFL1C
UniProt
Q9UNZ2
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant full length Human NSFL1C.
Clonality
Polyclonal
Applications
WB, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Reduces the ATPase activity of VCP (By similarity) . Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis (By similarity) . May play a role in VCP-mediated formation of transitional endoplasmic reticulum (tER) (By similarity) . Inhibits the activity of CTSL (in vitro) (PubMed:15498563) . Together with UBXN2B/p37, regulates the centrosomal levels of kinase AURKA/Aurora A during mitotic progression by promoting AURKA removal from centrosomes in prophase (PubMed:23649807) . Also, regulates spindle orientation during mitosis (PubMed:23649807) .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
40573 MW
Gene Name Synonym
NSFL1 cofactor p47
Subcellular Location
Nucleus
Protein Name
NSFL1 cofactor p47
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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