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Anti-NSFL1 cofactor p47 NSFL1C Antibody

Boster Bio Anti-NSFL1 cofactor p47 NSFL1C Antibody catalog # A08116. Tested in WB, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

NSFL1 cofactor p47; UBX domain-containing protein 2C; p97 cofactor p47; NSFL1C; UBXN2C

Gene Name

NSFL1C

UniProt

Q9UNZ2

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant full length Human NSFL1C.

Clonality

Polyclonal

Applications

WB, IF

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Reduces the ATPase activity of VCP (By similarity) . Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis (By similarity) . May play a role in VCP-mediated formation of transitional endoplasmic reticulum (tER) (By similarity) . Inhibits the activity of CTSL (in vitro) (PubMed:15498563) . Together with UBXN2B/p37, regulates the centrosomal levels of kinase AURKA/Aurora A during mitotic progression by promoting AURKA removal from centrosomes in prophase (PubMed:23649807) . Also, regulates spindle orientation during mitosis (PubMed:23649807) .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

40573 MW

Gene Name Synonym

NSFL1 cofactor p47

Subcellular Location

Nucleus

Protein Name

NSFL1 cofactor p47

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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