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Anti-PET112 Antibody (N-term)

Boster Bio Anti-PET112 Antibody (N-term) (Catalog # A08058) . Tested in WB application (s) . This antibody reacts with Human.

Product Specifications

Background

Allows the formation of correctly charged Gln-tRNA (Gln) through the transamidation of misacylated Glu-tRNA (Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA (Gln) .

Synonyms

Glutamyl-tRNA (Gln) amidotransferase subunit B, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03147}, Glu-AdT subunit B {ECO:0000255|HAMAP-Rule:MF_03147}, 635- {ECO:0000255|HAMAP-Rule:MF_03147}, Cytochrome c oxidase assembly factor PET112 homolog, GATB

Gene Name

GATB

UniProt

O75879

Host

Rabbit

Reactivity

Human

Immunogen

This PET112 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 25-60 amino acids from the N-terminal region of human PET112.

Clonality

Polyclonal

Tissue Specificity

Predominantly expressed in tissues characterized by high rates of oxidative phosphorylation (OxPhos), including muscle and heart.

Applications

WB

Field of Research

Metabolism, Mitochondria

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Allows the formation of correctly charged Gln-tRNA (Gln) through the transamidation of misacylated Glu-tRNA (Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA (Gln) .

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

61864 Da

Applications Notes

WB: 1:1000

Subcellular Location

Mitochondrion {ECO:0000255|HAMAP-Rule:MF_03147, ECO:0000269|PubMed:9878253}

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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