Anti-PPIE Antibody
Boster Bio Anti-PPIE Antibody catalog # A08021. Tested in WB, IP applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
Peptidyl-prolyl cis-trans isomerase E; PPIase E;5.2.1.8
Gene Name
PPIE
UniProt
Q9UNP9
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein of human PPIE (NP_006103.1) .
Clonality
Polyclonal
Tissue Specificity
Found in all the examined tissues including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
Applications
WB, IP
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Involved in pre-mRNA splicing as component of the spliceosome (PubMed:11991638, PubMed:28076346) . Combines RNA- binding and PPIase activities (PubMed:8977107, PubMed:18258190, PubMed:20677832, PubMed:20460131) . Binds mRNA and has a preference for single-stranded RNA molecules with poly-A and poly-U stretches, suggesting it binds to the poly (A) -region in the 3'-UTR of mRNA molecules (PubMed:8977107, PubMed:18258190, PubMed:20460131) . Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins (PubMed:8977107, PubMed:18258190, PubMed:20677832, PubMed:20541251) . Inhibits KMT2A activity; this requires proline isomerase activity (PubMed:20677832, PubMed:20541251, PubMed:20460131) .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
33431 MW
Gene Name Synonym
Peptidyl-prolyl cis-trans isomerase E
Subcellular Location
Nucleus
Protein Name
Peptidyl-prolyl cis-trans isomerase E
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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