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Anti-ECSIT Antibody (C-term)

Boster Bio Anti-ECSIT Antibody (C-term) (Catalog # A07966-1) . Tested in WB, IF application (s) . This antibody reacts with Human.

Product Specifications

Background

Adapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1. Promotes proteolytic activation of MAP3K1. Involved in the BMP signaling pathway. Required for normal embryonic development (By similarity) . Required for efficient assembly of mitochondrial NADH:ubiquinone oxidoreductase.

Synonyms

Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial, Protein SITPEC, ECSIT

Gene Name

ECSIT

UniProt

Q9BQ95

Host

Rabbit

Reactivity

Human

Immunogen

This ECSIT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 396-425 amino acids from the C-terminal region of human ECSIT.

Clonality

Polyclonal

Applications

WB, IF

Field of Research

Immunology, Signal Transduction, Innate Immunity, TLR Signaling, Mitochondria

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

25355951312817132535595125228397

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

49148 Da

Subcellular Location

Cytoplasm. Nucleus. Mitochondrion

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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