Anti-DNAJC10 Antibody
Boster Bio Anti-DNAJC10 Antibody catalog # A07954. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
DnaJ homolog subfamily C member 10;1.8.4.-; Endoplasmic reticulum DNA J domain-containing protein 5; ER-resident protein ERdj5; ERdj5; Macrothioredoxin; MTHr; DNAJC10; ERDJ5; UNQ495/PRO1012
Gene Name
DNAJC10
UniProt
Q8IXB1
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein of human DNAJC10 (NP_061854.1) .
Clonality
Polyclonal
Applications
WB, ICC, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins. Required for efficient folding of proteins in the endoplasmic reticulum by catalyzing the removal of non-native disulfide bonds formed during the folding of proteins, such as LDLR. Also involved in endoplasmic reticulum-associated degradation (ERAD) by reducing incorrect disulfide bonds in misfolded glycoproteins recognized by EDEM1. Interaction with HSPA5 is required its activity, not for the disulfide reductase activity, but to facilitate the release of DNAJC10 from its substrate. Promotes apoptotic signaling pathway in response to endoplasmic reticulum stress.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
91080 MW
Gene Name Synonym
DnaJ homolog subfamily C member 10
Subcellular Location
Endoplasmic reticulum lumen
Protein Name
DnaJ homolog subfamily C member 10
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
