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Anti-PAIP1 Antibody

Boster Bio Anti-PAIP1 Antibody catalog # A07792. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Polyadenylate-binding protein-interacting protein 1; PABP-interacting protein 1; PAIP-1; Poly (A) -binding protein-interacting protein 1; PAIP1

Gene Name

PAIP1

UniProt

Q9H074

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human PAIP1 (NP_877590.1) .

Clonality

Polyclonal

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Acts as a coactivator in the regulation of translation initiation of poly (A) -containing mRNAs. Its stimulatory activity on translation is mediated via its action on PABPC1. Competes with PAIP2 for binding to PABPC1. Its association with EIF4A and PABPC1 may potentiate contacts between mRNA termini. May also be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A07792

Product MSDS

https://www.bosterbio.com/msds?sku=A07792

Observed Molecular Weight

53525 MW

Applications Notes

WB: 1:500-1:1000

Gene Name Synonym

Polyadenylate-binding protein-interacting protein 1

Subcellular Location

Cytoplasm .

Protein Name

Polyadenylate-binding protein-interacting protein 1

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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