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Anti-TMC1 Antibody

Boster Bio Anti-TMC1 Antibody catalog # A07763-1. Tested in WB, IHC, IF, ELISA. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

Transmembrane channel-like protein 1 (TMC1), is an integral membrane protein with six transmembrane domains and cytoplasmically oriented N- and C- termini (PMID: 20672865) . Human TMC1 and mouse Tmc1 mRNA expression were detected in human fetal cochlea and inner-ear tissue of postnatal mouse, respectively. TMC1 is required for cochlear hair-cell function (PMID: 11850618) . It is a component of hair cell transduction channels and contributes to permeation properties (PMID: 23871232) . Mutations in TMC1 gene can cause progressive postlingual hearing loss and profound prelingual deafness (PMID: 11850618) . The antibody is specific to TMC1.

Gene Name

TMC1

UniProt

Q8TDI8

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Peptide

Clonality

Polyclonal

Applications

WB, IHC, IF, ELISA

Purification

Immunogen affinity purified.

Concentration

500 μg/mL

Form

Liquid

Storage Conditions

12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.

Contents

500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.

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