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Anti-PHF17 JADE1 Antibody

Boster Bio Anti-PHF17 JADE1 Antibody catalog # A07611. Tested in WB, IF applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Protein Jade-1; Jade family PHD finger protein 1; PHD finger protein 17; JADE1; KIAA1807, PHF17

Gene Name

JADE1

UniProt

Q6IE81

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Recombinant full length Human PHF17.

Clonality

Polyclonal

Tissue Specificity

Highly expressed in kidney. Also present in pancreas, liver and heart (at protein level) . Down-regulated in renal cancer cells.

Applications

WB, IF

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Component of the HBO1 complex which has a histone H4- specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Transcriptional coactivator, it may also promote acetylation of nucleosomal histone H4 by KAT5. Promotes apoptosis. May act as a renal tumor suppressor. Negatively regulates canonical Wnt signaling; at least in part, cooperates with NPHP4 in this function.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

95533 MW

Gene Name Synonym

Protein Jade-1

Subcellular Location

Cytoplasm

Protein Name

Protein Jade-1

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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