Anti-RTCD1 RTCA Antibody
Boster Bio Anti-RTCD1 RTCA Antibody catalog # A07570. Tested in WB, IHC applications. This antibody reacts with Human, Rat.
Product Specifications
Synonyms
RNA 3'-terminal phosphate cyclase; RNA cyclase; RNA-3'-phosphate cyclase;6.5.1.4; RNA terminal phosphate cyclase domain-containing protein 1; RTC domain-containing protein 1; RTCA; RPC, RPC1, RTC1, RTCD1
Gene Name
RTCA
UniProt
O00442
Host
Rabbit
Reactivity
Human, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 321-366 of Human RTCD1.
Clonality
Polyclonal
Tissue Specificity
Ubiquitous.
Applications
WB, IHC
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA- N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'- phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
39337 MW
Gene Name Synonym
RNA 3'-terminal phosphate cyclase
Subcellular Location
Nucleus, nucleoplasm.
Protein Name
RNA 3'-terminal phosphate cyclase
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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