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Anti-NOSIP Antibody

Boster Bio Anti-NOSIP Antibody catalog # A07558. Tested in WB applications. This antibody reacts with Human.

Product Specifications

Synonyms

Nitric oxide synthase-interacting protein; E3 ubiquitin-protein ligase NOSIP;2.3.2.27; RING-type E3 ubiquitin transferase NOSIP ; eNOS-interacting protein; NOSIP; CGI-25

Gene Name

NOSIP

UniProt

Q9Y314

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant fusion protein of human NOSIP (NP_057037.1) .

Clonality

Polyclonal

Tissue Specificity

Expressed in heart, brain and lung. Present in endothelial cells (at protein level) .

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

E3 ubiquitin-protein ligase that is essential for proper development of the forebrain, the eye, and the face. Catalyzes monoubiquitination of serine/threonine-protein phosphatase 2A (PP2A) catalytic subunit PPP2CA/PPP2CB (By similarity) . Negatively regulates nitric oxide production by inducing NOS1 and NOS3 translocation to actin cytoskeleton and inhibiting their enzymatic activity (PubMed:11149895, PubMed:15548660, PubMed:16135813) .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A07558

Product MSDS

https://www.bosterbio.com/msds?sku=A07558

Observed Molecular Weight

33172 MW

Applications Notes

WB: 1:500-1:2000

Gene Name Synonym

Nitric oxide synthase-interacting protein

Subcellular Location

Cytoplasm

Protein Name

Nitric oxide synthase-interacting protein

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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