Anti-SARA/ZFYVE9 Antibody
Boster Bio Anti-SARA/ZFYVE9 Antibody catalog # A07533-1. Tested in WB, IHC, IF, IP, ELISA applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Background
ZFYVE9, also known as SARA (Smad anchor for receptor activation), is a double zinc finger (FYVE domain) protein that interacts directly with SMAD2 and SMAD3, and is involved in Alzheimer's disease. SARA functions to recruit SMAD2/SMAD3 to intracellular membranes and to the TGF-beta receptor. SARA plays a significant role in TGF-mediated signaling by regulating the subcellular location of SMAD2 and SMAD3 and modulating the transcriptional activity of the SMAD3/SMAD4 complex. SARA is possibly associated with TGF-beta receptor internalization.
Gene Name
ZFYVE9
UniProt
O95405
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
E.coli-derived human SARA/ZFYVE9 recombinant protein (Position: R1077-E1422) .
Clonality
Polyclonal
Applications
WB, IHC, IF, IP, ELISA
Purification
Immunogen affinity purified.
Concentration
500 μg/mL
Form
Liquid
Storage Conditions
12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.
Contents
500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.
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