Anti-HINFP Antibody (Center)
Boster Bio Anti-HINFP Antibody (Center) (Catalog # A07517) . Tested in WB application (s) . This antibody reacts with Human, Mouse.
Product Specifications
Background
MIZF interacts with methyl-CpG-binding protein-2 (MBD2; MIM 603547), a component of the MeCP1 histone deacetylase (HDAC) complex, and plays a role in DNA methylation and transcription repression.
Synonyms
Histone H4 transcription factor, Histone nuclear factor P, HiNF-P, MBD2-interacting zinc finger protein, Methyl-CpG-binding protein 2-interacting zinc finger protein, HINFP, MIZF, ZNF743
Gene Name
HINFP
UniProt
Q9BQA5
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This HINFP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 317-346 amino acids from the Central region of human HINFP.
Clonality
Polyclonal
Tissue Specificity
Ubiquitous. Highly expressed in brain, heart, skeletal muscle, spleen, kidney, small intestine, placenta and liver
Applications
WB
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Transcriptional repressor that binds to the consensus sequence 5'-CGGACGTT-3' and to the RB1 promoter. Transcriptional activator that promotes histone H4 gene transcription at the G1/S phase transition in conjunction with NPAT. Also activates transcription of the ATM and PRKDC genes. Autoregulates its expression by associating with its own promoter.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight
59678 Da
Applications Notes
WB: 1:1000
Subcellular Location
Nucleus. Note=Associated with discrete nuclear foci
Isotype
Rabbit IgG
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
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