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Anti-TFIP11 Antibody

Boster Bio Anti-TFIP11 Antibody catalog # A07513. Tested in WB applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Tuftelin-interacting protein 11; Septin and tuftelin-interacting protein 1; STIP-1; TFIP11; STIP; HSPC006

Gene Name

TFIP11

UniProt

Q9UBB9

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Recombinant protein of human TFIP11

Clonality

Polyclonal

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS) . In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP-containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extracellular matrix.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

96820 MW

Applications Notes

WB: 1:200-1:3000

Gene Name Synonym

Tuftelin-interacting protein 11

Subcellular Location

Cytoplasm . Nucleus . In the nucleus localizes to unique speckle domains in close proximity to nuclear speckles and not identical to paraspeckles. .

Protein Name

Tuftelin-interacting protein 11

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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