Anti-TMX1 Antibody
Boster Bio Anti-TMX1 Antibody catalog # A07462-2. Tested in WB, IHC, ELISA applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Background
TMX1, one of the few transmembrane members of the family, is the first vascular thiol isomerase with antithrombotic function. It forms functional complexes with the ER lectin calnexin and preferentially intervenes during maturation of cysteine-containing, membrane-associated proteins while ignoring the same cysteine-containing ectodomains if not anchored at the ER membrane. As such, TMX1 is the first example of a topology-specific client protein redox catalyst in living cells (PMID: 30655304) . Covalent modification with AMS increases the molecular mass of originally oxidized species by ~0.5 kDa per thiol group, which allows enhanced separation from the reduced form in electrophoresis (PMID: 29123984) . TMX1 has 2 bands produces by redox with the MW of 30-32 kDa.
Gene Name
TMX1
UniProt
Q9H3N1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
E.coli-derived human TMX1 recombinant protein (Position: D204-T277) .
Clonality
Polyclonal
Applications
WB, IHC, ELISA
Purification
Immunogen affinity purified.
Concentration
500 μg/mL
Form
Liquid
Storage Conditions
12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.
Contents
500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.
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