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Anti-CTDSP1 Antibody

Boster Bio Anti-CTDSP1 Antibody catalog # A07398. Tested in WB, IP applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1;3.1.3.16

Gene Name

CTDSP1

UniProt

Q9GZU7

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding Human CTDSP1.

Clonality

Polyclonal

Tissue Specificity

Expression is restricted to non-neuronal tissues. Highest expression in skeletal muscle, spleen, lung and placenta.

Applications

WB, IP

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Preferentially catalyzes the dephosphorylation of 'Ser- 5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

29203 MW

Gene Name Synonym

Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

Subcellular Location

Nucleus

Protein Name

Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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