Anti-Tensin-3 TNS3 Antibody
Boster Bio Anti-Tensin-3 TNS3 Antibody catalog # A07345. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Tensin-3; Tensin-like SH2 domain-containing protein 1; Tumor endothelial marker 6; TNS3; TEM6, TENS1, TPP
Gene Name
TNS3
UniProt
Q68CZ2
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 535-580 of Human TNS3.
Clonality
Polyclonal
Tissue Specificity
Expressed in umbilical vein endothelial cells, epithelial cells, and fibroblasts cells (at protein level) . Highly expressed in thyroid, kidney and placenta. Low expression in heart, skeletal muscle, spleen, liver, and lung. Expressed in tumor endothelial cells. Expression seems to be down-regulated in thyroid tumor tissues and in anaplastic carcinomas.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
May play a role in actin remodeling. Involved in the dissociation of the integrin-tensin-actin complex. EGF activates TNS4 and down-regulates TNS3 which results in capping the tail of ITGB1. Seems to be involved in mammary cell migration. May be involved in cell migration and bone development (By similarity) .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
155266 MW
Applications Notes
WB: 1:500-1:1000
Gene Name Synonym
Tensin-3
Subcellular Location
Cell junction, focal adhesion
Protein Name
Tensin-3
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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