Anti-Serpin B6 Antibody
Boster Bio Anti-Serpin B6 Antibody catalog # A07155. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Serpin B6; Cytoplasmic antiproteinase; CAP; Peptidase inhibitor 6; PI-6; Placental thrombin inhibitor; SERPINB6; PI6, PTI
Gene Name
SERPINB6
UniProt
P35237
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human SERPINB6 (NP_004559.4) .
Clonality
Polyclonal
Tissue Specificity
Expressed in keratinocytes (at protein level) . Highest levels in skeletal muscle. Also found in placenta, cardiac muscle, lung, liver, kidney and pancreas. Expressed in the inner ear hair cells. Expressed abundantly by normal mast cells in different tissues and by mast cells in mastocytoma lesions.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
May be involved in the regulation of serine proteinases present in the brain or extravasated from the blood (By similarity) . Inhibitor of cathepsin G, kallikrein-8 and thrombin. May play an important role in the inner ear in the protection against leakage of lysosomal content during stress and loss of this protection results in cell death and sensorineural hearing loss.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
42622 MW
Applications Notes
WB: 1:500-1:2000
Gene Name Synonym
Serpin B6
Subcellular Location
Cytoplasm
Protein Name
Serpin B6
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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