Anti-CCL14/Hcc 1 Antibody
Boster Bio Anti-CCL14/Hcc 1 Antibody catalog # A07151. Tested in IHC, IF, ELISA applications. This antibody reacts with Human.
Product Specifications
Synonyms
C-C motif chemokine 14; Chemokine CC-1/CC-3; HCC-1/HCC-3; HCC-1 (1-74) ; NCC-2; Small-inducible cytokine A14; HCC-1 (3-74) ; HCC-1 (4-74) ; HCC-1 (9-74) ; CCL14; NCC2, SCYA14
Gene Name
CCL14
UniProt
Q16627
Host
Rabbit
Reactivity
Human
Immunogen
Synthetic peptide from human protein at AA range: 44-93
Tissue Specificity
Expressed constitutively in several normal tissues: spleen, liver, skeletal and heart muscle, gut, and bone marrow, present at high concentrations (1-80 nM) in plasma. .
Applications
IHC, IF, ELISA
Purification
Immunogen affinity purified
Concentration
1 mg/mL
Form
Liquid
Function
Has weak activities on human monocytes and acts via receptors that also recognize MIP-1 alpha. It induced intracellular Ca (2+) changes and enzyme release, but no chemotaxis, at concentrations of 100-1,000 nM, and was inactive on T-lymphocytes, neutrophils, and eosinophil leukocytes. Enhances the proliferation of CD34 myeloid progenitor cells. The processed form HCC-1 (9-74) is a chemotactic factor that attracts monocytes eosinophils, and T-cells and is a ligand for CCR1, CCR3 and CCR5. .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
10678 MW
Gene Name Synonym
C-C motif chemokine 14
Subcellular Location
Secreted.
Isotype
IgG
Contents
PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
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